A comparison of the acute haemodynamic effects of thiopentone, methohexitone and propanidid in the dog.

Studies of anaesthesia in relation to hypertension. II: Hemodynamic consequences of induction and endotracheal intubation. 1971.

The electrocardiographic and haemodynamic responses to the induction of anaesthesia, followed by laryngoscopy and endotracheal intubation have been studied in a group of 16 untreated hypertensive patients, and a group of 20 patients receiving antihypertensive therapy up to and including the day of operation. The influence of five different induction agents, thiopentone, methohexitone, propanidi...

Changes in haemodynamic variables with thiopentone, methohexitone, propofol and etomidate.

A technique for the laboratory evaluation of the speed of onset of I.V. anaesthesia.

A method is described for the evaluation of the speed of onset of i.v. anaesthesia in mice. The technique involves (a) determination of the median hypnotic dose (HD50) by plotting the probit value of the percentage of mice sleeping, against dose on a logarithmic scale, (b) plotting mean induction time over a range of doses against the logarithm of the dose and (c) comparison of induction times ...

Cardiovascular effects of short-term anaesthesia with methohexitone and propanidid in normal subjects.

The cardiovascular effects of a single dose of two short-acting intravenous anaesthetics, methohexitone and propanidid, were studied in ten healthy male volunteers. The doses used were selected to produce clinical anaesthesia of similar depth and duration. Methohexitone increased heart rate initially without changing arterial or filling pressures. The C(a-v)02 difference was decreased, suggesti...

Value of Propanidid in Electro Convulsive Therapy (comparison with Thiopentone)

Propanidid due to its fast induction, early recovery and absence of cumulative action avoiding post recovery hangover is a useful agent and a better substitute for the established inducing agent, thiopentone It has all the advantages of thiopentone but lacks tbe disadvantages of the same. Its extremely short duration of action suits the short procedure of electroconvulsive therapy which gets ov...